|
Symbol Name ID |
Gad1
glutamate decarboxylase 1 MGI:95632 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Spasticity |
Hypoplasia of the corpus callosum |
Cerebral atrophy |
Cerebellar atrophy |
Tetraparesis |
EEG abnormality |
EEG with burst suppression |
Hypsarrhythmia |
Delusion |
Schizophrenia |
Hallucinations |
Negativism |
Addictive alcohol use |
Social and occupational deterioration |
Intellectual disability, profound |
Hyperreflexia |
Dystonia |
Hyperkinetic movements |
Global developmental delay |
Bilateral tonic-clonic seizure with generalized onset |
Epileptic spasm |
Myoclonic seizure |
| Disease(s) Associated with GAD1 | ||||||||||||||||||||||
| alcohol dependence | ||||||||||||||||||||||
| developmental and epileptic encephalopathy 89 | ||||||||||||||||||||||
| schizophrenia |
| Mouse Phenotypes | nervous system phenotype |
abnormal nervous system morphology |
abnormal brain interneuron morphology |
abnormal visual cortex morphology |
abnormal nervous system electrophysiology |
abnormal GABA-mediated receptor currents |
abnormal inhibitory postsynaptic currents |
decreased prepulse inhibition |
|
| Availability | Mouse Genotype | ||||||||
| Gad1tm1Tama/Gad1tm1Tama | |||||||||
| Gad1tm1.1Rpa/Gad1+ | |||||||||
| Gad1tm1.1Tama/Gad1+ | * | ||||||||
| Tg(Pvalb-tdTomato/RNAi:Gad1)3Mirn/? | |||||||||
| Gad1tm1Rpa/Gad1tm1Rpa (conditional) | |||||||||
| Gad1tm2Oba/Gad1tm2Oba Ptf1atm1.1(cre)Cvw/Ptf1a+ (conditional) |
|||||||||
| Gad1tm1Rpa/Gad1+ (conditional) | |||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools